trusted by 100+ Patients
Dihexa
About the Treatment
What Is Dihexa?
Dihexa is developed to support brain health, memory, and learning. It was designed to reach the brain directly and help strengthen the connections between brain cells. Early research suggests Dihexa may support mental clarity, focus, and long-term cognitive function by improving how brain cells communicate.
Researchers are particularly interested in Dihexa because it works differently from typical brain-boosting compounds. Instead of creating a short-term stimulant effect, it is studied for its potential to support long-lasting improvements in memory and learning by helping the brain form and maintain stronger neural connections
Key Benefits
Dihexa Benefits
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Supports Synaptic Plasticity
Research suggests Dihexa promotes synaptic plasticity by strengthening synapses and supporting the formation of new synaptic connections between neurons.
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May Enhance Memory and Learning
Animal models demonstrate improvements in memory, spatial learning, focus, and cognitive enhancement without stimulant-like effects.
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Supports Brain Health and Neuroprotection
Dihexa has been studied for potential neuroprotective effects, including reduced apoptosis (programmed cell death) in neurons under stress.
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Investigated in Cognitive Decline Model
Research use includes models of cognitive decline, aging, dementia, and neurodegenerative diseases.
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Non-Stimulatory Mechanism
Rather than acting like traditional cognitive drugs, Dihexa influences structural brain pathways related to cognition and long-term neural stability.
Advanced diagnostics. Regenerative therapies. Personalised wellness plans.
Advanced diagnostics. Regenerative therapies. Personalised wellness plans.
FAQs
01
Is Dihexa approved for human use?
No. Dihexa (blood-brain-barrier permeable angiotensin IV analog) is not approved for routine human treatment and is classified strictly for research use. Most findings come from animal models rather than large-scale human trials. Regulatory approval has not been established for patients.
02
Where did Dihexa research originate?
Dihexa is structurally classified as an aminohexanoic amide (N-hexanoic Tyr-Ile) and is designed to be orally active, with the ability to cross the blood–brain barrier. Preclinical analysis at Washington State University suggests Dihexa binds with high affinity to hepatocyte growth factor (HGF) and enhances signaling through the c-Met receptor.
03
How does Dihexa affect cognitive function?
Research suggests Dihexa binds to hepatocyte growth factor with high affinity and activates the c-Met receptor, influencing pathways responsible for cell growth, synapse formation, and neural connectivity. These mechanisms may support memory enhancement, learning, and cognitive improvement.
04
Can Dihexa cross the blood–brain barrier?
Yes. Dihexa was specifically designed to cross the blood–brain barrier, allowing it to act directly within the brain and central nervous system. In preclinical studies, Dihexa has been shown to be millions of times more potent than Brain-Derived Neurotrophic Factor (BDNF) at stimulating synapse formation.
05
What conditions has Dihexa been studied for?
Preclinical research has explored Dihexa in models related to Alzheimer’s disease, dementia, cognitive decline associated with aging, traumatic brain injury, stroke recovery, Parkinson’s disease, and neurodegenerative diseases affecting memory and cognition.
06
What evidence exists from animal studies?
In experiments involving rats and other animals, Dihexa demonstrated excellent anti-dementia activity, improved spatial learning, memory retention, and synaptic density. Furthermore, Dihexa has demonstrated the ability to decrease levels of pro-inflammatory cytokines in animal models, indicating potential anti-inflammatory effects.
07
Does Dihexa influence mood or anxiety?
Some animal studies observed changes in mood-related behaviors, including reduced anxiety-like responses, likely linked to improved neural signaling and synaptic stability. Human outcomes remain undetermined.
08
How is Dihexa different from traditional cognitive drugs?
Unlike many drugs that increase neurotransmitter release, Dihexa works through a structural mechanism, stimulating neural connections, synapses, and neuroplasticity rather than temporary stimulation.
09
Is Dihexa considered neuroprotective?
Preclinical data suggest potential neuroprotective effects, including protection of neurons from apoptosis and damage associated with inflammation, aging, and disease progression. Furthermore, Dihexa has been linked to the activation of the PI3K/AKT signaling pathway, which is important for neuronal survival and function.
10
Can Dihexa help with traumatic brain injury or stroke recovery?
Animal experiments have explored Dihexa’s role in recovery following traumatic brain injury and stroke, showing improved cognitive outcomes and neural repair pathways.