What if the key to unlocking more energy, sharper focus, and healthier ageing already existed within your cells?

As interest in regenerative medicine and longevity therapies grows, one molecule is consistently at the centre of the conversation: nicotinamide adenine dinucleotide (NAD). This naturally occurring coenzyme plays a vital role in energy metabolism and cellular repair, yet its levels decline with age, stress, and chronic illness.

From boosting brain function to addressing the aging process, NAD IV therapy is being explored as a powerful tool to support the body's natural ability to heal, regenerate, and perform at its best. 

But how does it work? And what does the science really say?

What is NAD+?

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every living cell. It plays a central role in cellular metabolism, acting as a carrier for electrons during metabolic reactions that create ATP — the body's primary energy currency. In simpler terms, NAD+ is essential for energy production at the most fundamental, cellular level.

But NAD+ isn’t just about fuelling the body. It’s also a key player in cellular repair, DNA maintenance, and gene expression. It supports enzymes called sirtuins and PARPs, which regulate everything from inflammation to cellular regeneration, and help slow the onset of cellular senescence — the biological ageing of cells.

Unfortunately, NAD levels naturally decline with age, environmental toxins, poor lifestyle choices, and chronic disease. This decline is associated with reduced mitochondrial function, impaired immune system performance, and slower metabolic processes. These factors contribute to the age-related decline in everything from mental clarity and muscle function to skin health and overall well-being.

The Science Behind NAD+ and Cellular Function

NAD+ is deeply integrated into the body’s ability to adapt, defend, and regenerate. One of its most critical contributions lies in its involvement with enzymes that support cognitive function, regulate inflammatory pathways, and influence how cells age, divide, or repair themselves.

For example, NAD+ is essential for activating sirtuins — proteins that play a key role in maintaining genomic stability and orchestrating the body’s response to metabolic and environmental stress. These proteins are strongly associated with longevity and cellular resilience.

In the brain, NAD+ helps preserve mental clarity by fuelling the metabolic demands of neurons and assisting in neurotransmitter function. This has made it a focus of research in neurodegenerative conditions, addiction recovery, and sleep disorders.

Its influence extends to immune function as well, where it supports the energy demands of immune cells and helps regulate inflammatory responses. Some studies suggest NAD+ may also have applications in managing autoimmune diseases and reducing chronic inflammation at a cellular level.

Why IV Therapy Instead of Oral Supplements?

While NAD+ is available in supplement form, its absorption through the digestive system is limited. The coenzyme must undergo conversion in the gut and liver, which significantly reduces its potency before it reaches the bloodstream. This is one reason oral supplementation often leads to inconsistent results.

IV therapy, on the other hand, delivers NAD+ directly into the bloodstream — bypassing the gastrointestinal tract entirely. This ensures maximum bioavailability and allows for higher therapeutic doses to be administered safely and effectively. Because the coenzyme enters circulation immediately, patients often report feeling the benefits of NAD within hours or days rather than weeks. These include boosted energy, reduced fatigue, and enhanced focus. For individuals with compromised gut health or chronic inflammation, NAD+ delivered via IV drip is especially advantageous.

Additionally, healthcare providers can combine NAD IV therapy with other nutrients, such as amino acids, antioxidants, and vitamins, to support cellular repair and overall vitality.

Who Might Benefit from NAD IV Therapy?

High Performers and Executives

NAD+ supports sharper focus, faster thinking, and mental stamina under pressure. For professionals facing cognitive fatigue or burnout, IV therapy can help enhance brain function and maintain peak performance during demanding periods.

Ageing Individuals

As NAD levels naturally decline with age, many experience slower recovery, reduced vitality, and changes in skin and energy. NAD IV therapy helps address aging at the cellular level, supporting skin health, cellular health, and mitochondrial efficiency for more graceful ageing.

Athletes and Fitness Enthusiasts

Physical exertion depletes cellular resources. NAD+ supports muscle function, quicker muscle recovery, and metabolic resilience. Athletes may benefit from improved cellular energy, less downtime between sessions, and enhanced endurance.

Those With Chronic Fatigue or Burnout

Fatigue isn’t always solved with rest. When caused by depleted cellular energy production or chronic stress, NAD therapy offers support by helping cells restore function and boosting energy levels naturally.

Individuals With Metabolic or Inflammatory Conditions

People dealing with insulin resistance, fatty liver disease, or chronic inflammation may benefit from the therapy’s ability to improve metabolic functions, regulate immune response, and restore internal balance.

What to Expect During a NAD IV Treatment

Every NAD IV experience should begin with a personalised consultation to assess your needs, baseline cellular health, and suitability for treatment. Your NAD IV therapy sessions will be tailored to your goals — whether that’s improving recovery, supporting cognitive function, or addressing signs of skin ageing.

The Infusion Process

A NAD infusion typically lasts between 60 to 90 minutes, depending on the dose and individual tolerance. Because NAD+ can stimulate cellular activity quickly, some people may feel sensations such as chest tightness, flushing, or slight nausea if the drip is administered too fast. That’s why experienced providers deliver NAD slowly and adjust the rate for comfort.

During the Session

Many clients report a sense of calm focus or even an “internal recharge” during and after the session. Over a series of treatments, the benefits of NAD IV may include improved mood, enhanced mental clarity, and increased energy as NAD IV therapy works to restore mitochondrial efficiency and regulate the body’s stress response.

Is NAD IV Therapy Safe?

When administered by a qualified healthcare provider, NAD IV therapy is safe and well-tolerated. Side effects are minimal and usually related to infusion speed. A proper medical assessment is essential to ensure you’re a good candidate for treatment and to avoid contraindications.

Recommended Frequency

Some individuals feel noticeable improvements after a single infusion, while others benefit from a structured programme of regular sessions. The frequency and dosing depend on your goals.

NAD IV Therapy at Vervé Wellness

At Vervé Wellness, each client begins with an in-depth diagnostic assessment to understand their current NAD levels, cellular function, and overall biological state. From there, a bespoke treatment plan is created, integrating NAD IV therapy sessions into a broader protocol that may also include IV micronutrients, peptide therapy, hormone optimisation, and advanced longevity coaching.

Our medical team ensures that NAD IV therapy is safe, effective, and tailored to your unique biology. Infusions are delivered at a pace that matches your comfort and physiology — whether you’re looking to improve energy, enhance brain health, or support long-term overall well-being.

Treatments are available in-clinic or via concierge service, allowing you to receive expert care from the comfort of your home, office, or while travelling. At Vervé Wellness, NAD+ is not just a molecule — it’s part of a wider mission to transform how you age, perform, and feel.

The Growing Role of NAD+ in Longevity and Regenerative Medicine

NAD+ is no longer a niche molecule tucked away in biochemistry textbooks — it’s now central to some of the most advanced strategies in anti-aging and regenerative health.

As science continues to uncover the potential benefits of supporting cellular health through NAD+ replenishment, clinics and researchers are exploring how it influences everything from gene repair to immune resilience. By enhancing mitochondrial efficiency and fuelling cellular regeneration, NAD+ plays a critical role in helping the body perform optimally — not just today, but for the long haul.

What sets NAD therapy apart is its influence across multiple systems. It helps regulate the stress response, preserve brain health, promote overall health, and reduce the pace of cellular decline associated with ageing. This multi-targeted effect is why many integrative medicine clinics now combine NAD with other therapies to amplify outcomes.

The benefits of NAD IV extend beyond just symptom relief. Patients are often looking to enhance performance, protect against cognitive decline, or invest in long-term vitality. And as clinical research grows, so does the case for NAD+ as a core component of future-focused wellness.

Whether you’re addressing skin ageing, working to enhance mental clarity, or aiming to maintain improved cognitive function as you age — NAD+ is fast becoming a cornerstone of the modern approach to overall wellness, increased energy, and even DNA repair. Its ability to activate key enzymes involved in maintaining genome stability makes it a powerful ally in the pursuit of long-term health and vitality.

At Vervé Wellness, this isn’t just about one molecule — it’s about personalised transformation, led by science and delivered with care.

Book your personalised NAD IV consultation at Vervé Wellness today.‍